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IMPAACT 2002

Combined Cognitive Behavioral Therapy and a Medication Management Algorithm for Treatment of Depression among Youth Living with HIV in the United States

Study Status

Participants Off Study and Primary Analysis Completed

DAIDS Number

12051

IND Number

Non-IND

Summary

IMPAACT 2002 is multi-site, two-arm, cluster-randomized study to examine if a Health and Wellness Cognitive Behavioral Therapy and Medication Management for depression improves outcomes for HIV-infected youth in the United States. Approximately 130 HIV-infected youth, ages 14-24 with depression, will be assigned to either Health and Wellness Cognitive Behavioral Therapy and Medication Management group or the Enhanced Standard of Care group and followed for 48 weeks. The study will examine whether participants receiving Health and Wellness Cognitive Behavioral Therapy and Medication Management Algorithm treatment for depression demonstrate improved depression outcomes and improved biological measures of health compared to participants receiving the Enhanced Standard of Care therapy.

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