Manuscripts
Showing 1530 manuscripts.
Antiretroviral choice and severe disease predict poorer neuropsychological outcomes in HIV+ children from Africa
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Lee Fairlie, Miriam Chernoff, Mark F. Cotton, Mutsa Bwakura-Dangarembizi, Avy Violari, Itziar Familiar-Lopez, Linda Barlow-Mosha, Portia Kamthunzi, Katie Mccarthy, Patrick Jean-Philippe, Barbara Laughton, Paul E Palumbo, Michael J Boivin. Antiretroviral choice and severe disease predict poorer neuropsychological outcomes in HIV+ children from Africa. Frontiers in Pediatrics. 2022. 10: 899002. PMID: 35989995
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Growth deficits in antiretroviral and HIV-exposed uninfected versus unexposed children in Malawi and Uganda persist through 60 months of age.
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Fowler MG, Aizire J, Sikorskii A, Atuhaire P, Ogwang LW, Mutebe A, Katumbi C, Maliwichi L, Familiar I, Taha T, Boivin MJ, PROMISE-NEURODEV study team. Growth deficits in antiretroviral and HIV-exposed uninfected versus unexposed children in Malawi and Uganda persist through 60 months of age.. AIDS. 2022. 36: 573-582. PMID: 34750297
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SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway.
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Campbell GR, To RK, Hanna J, Spector SA. SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway.. iScience. 2021. 24: 102295. PMID: 33718825
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High Prevalence of Tuberculosis Infection and Disease in Child Household Contacts of Adults With Rifampin-resistant Tuberculosis
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Kim S, Wu X, Hughes MD, Upton C, Narunsky K, Mendoza-Ticona A, Khajenoori S, Gonzales P, Badal-Faesen S, Shenje J, Omoz-Oarhe A, Rouzier V, Garcia-Prats AJ, Demers AM, Naini L, Smith E, Churchyard G, Swindells S, Shah NS, Gupta A, Hesseling AC, ACTG A5300/IMPAACT 2003/PHOENix Feasibility Study Team. High Prevalence of Tuberculosis Infection and Disease in Child Household Contacts of Adults With Rifampin-resistant Tuberculosis. Pediatric Infectious Disease Journal. 2022. 41: 194-202. PMID: 35239624
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Host transcriptomic signatures of tuberculosis can predict immune reconstitution inflammatory syndrome in HIV patients.
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Mbandi SK, Painter H, Penn-Nicholson A, Toefy A, Erasmus M, Hanekom WA, Scriba TJ, Lai RPJ, Marais S, Fletcher HA, Meintjes G, Wilkinson RJ, Cotton MF, Pahwa S, Cameron MJ, Nemes E. Host transcriptomic signatures of tuberculosis can predict immune reconstitution inflammatory syndrome in HIV patients.. European Journal of Immunology. 2022. 52: 1112-1119. PMID: 35398886
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Current strategies to induce selective killing of HIV-1-infected cells.
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Campbell GR, Spector SA. Current strategies to induce selective killing of HIV-1-infected cells.. Journal of Leukocyte Biology. 2022. PMID: 35707952Journal
Pharmacokinetics, safety, tolerability and antiviral activity of dolutegravir dispersible tablets in infants and children with HIV-1: results of the IMPAACT P1093 study, a phase I/II open-label trial
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Theodore D. Ruel, Edward P. Acosta, Jessica P. Liu, Kathryn P. Gray, Kathleen George, Nicole MontaƱez, Stephanie Popson, Ann M. Buchanan, Mattie Bartlett, Dale Dayton, Patricia Anthony, Cynthia Brothers, Cynthia Vavro, Rajendra Singh, Lucy Koech, Tichaona Vhembo, Rohan Hazra, Ellen Townley, Andrew Wiznia, IMPAACT P1093 Team. Pharmacokinetics, safety, tolerability and antiviral activity of dolutegravir dispersible tablets in infants and children with HIV-1: results of the IMPAACT P1093 study, a phase I/II open-label trial. Lancet HIV. 2022. PMID: 35489377
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Leveraging physiologically based pharmacokinetic modeling to optimize dosing for lopinavir/ritonavir with rifampin in pediatric patients
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Sara N Salerno, Edmund V Capparelli, Helen McIlleron, Jacqueline G Gerhart, Julie B Dumond, Angela D M Kashuba, Paolo Denti, Daniel Gonzalez. Leveraging physiologically based pharmacokinetic modeling to optimize dosing for lopinavir/ritonavir with rifampin in pediatric patients. Journal of the American College of Clinical Pharmacy. 2022. PMID: 35607886Journal
Interactions between etonogestrel-releasing contraceptive implant and 3 antiretroviral regimens
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Regis Kreitchmann, Alice Stek, Brookie M Best, Edmund Capparelli, Jiajia Wang, David Shapiro, Nahida Chakhtoura, Mark Mirochnick, Ahizechukwu C Eke, IMPAACT P1026s protocol team. Interactions between etonogestrel-releasing contraceptive implant and 3 antiretroviral regimens. Contraception. 2022. 105: 67-74. PMID: 34407424
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Validation and application of a quantitative liquid chromatography tandem mass spectrometry assay for the analysis of rifapentine and 25-O-desacetyl rifapentine in human milk
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Buyisile Mkhize, Tracy Kellermann, Jennifer Norman, Sandra Castel, Anton Joubert, Kelly E. Dooley, Jyoti S. Mathad, Lubbe Wiesner. Validation and application of a quantitative liquid chromatography tandem mass spectrometry assay for the analysis of rifapentine and 25-O-desacetyl rifapentine in human milk. Journal of Pharmaceutical and Biomedical Analysis. 2022. 215PMID: 35462285