Brain & Mental Health


The IMPAACT Brain and Mental Health Scientific Committee (formerly HIV Complications & Co-morbidities Scientific Committee) aims to determine optimal and feasible biological and behavioral methods for the prevention and management of neuropsychological and mental health complications of HIV and its treatment in infants, children, adolescents, and pregnant and postpartum people. 




Priorities include the evaluation of:

  • Investigate potential neuroprotective and neurotoxic effects of ART to preserve neurocognitive development and mental health in infants, children, and adolescents 
  • Refine and optimize evaluation and treatment of neurocognitive and mental health disorders, particularly executive dysfunction, depression, and PTSD 
  • Evaluate novel preventive and/or therapeutic approaches for high-priority diseases of importance related to brain and mental health within pediatric, adolescent, and pregnant/postpartum populations with or affected by HIV, working with other partners and NIH Institutes 

Learn more about the current portfolio and prior research from the Complications & Co-Morbidities Scientific Committee.


Committee Contacts

Chair: Jackie Hoare
Vice-Chair: Megan McHenry
Operations Center: Haley Brozik, Sarah BuissonElizabeth Rivas




Up Next:

The IMPAACT Cure & Immunology Scientific Committee aims to evaluate the potential for ART-free HIV remission through therapeutic interventions aimed at prevention, clearance, and post-treatment control of HIV reservoirs in infants, children, and adolescents with HIV and leverage expertise for evaluation of vaccines for HIV and related/co-occurring conditions in these populations.