Our Mission

Our mission is to improve health outcomes in infancy, childhood, adolescence, pregnancy, and postpartum among those who are impacted by or living with HIV by evaluating novel treatments and interventions for HIV, tuberculosis, and other related complications.

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Quick Links

RFP: Use of IMPAACT 2028 Data and Specimens

The IMPAACT Network is now accepting proposals for use of data and/or specimens collected in IMPAACT 2028, Long-Term Clinical, Immunologic, and Virologic Profiles of Children who Received Early Treatment for HIV. Please visit the Research & Study Opportunities page linked below for more information and application materials. Applications are due by 21 August 2026.

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News

Dr. Edmund Capparelli Receives AACP Award

June 2026

Announcements

Dr. Edmund Capparelli Honored with Award from ACCP

Call for Applications: Early Career Investigator Program 2026-2028 Cycle

March 2026

Announcements

Call for Applications: Early Career Investigator Program 2026-2028 Cycle

February 2026

Announcements

IMPAACT at CROI 2026

Research Areas

The IMPAACT Network is committed to conducting high-quality clinical trials to support our mission globally. Our research agenda includes four scientific specific aims.

Cure & Immunotherapy

Brain & Mental Health

Therapeutics

Tuberculosis

Studies

active studies

The IMPAACT Network is always working on many studies at one time in the areas of treatment, tuberculosis, ART-free remission, and complications.

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Study Snapshot

This document highlights major steps in protocol implementation and gives a quick look at accrual for each study. It is updated monthly.

Submit Study Proposals

Proposals for new IMPAACT studies may be submitted by internal or external investigators in the form of a concept sheet any time.

IMPAACT Community Engagement

Community participation and engagement are critical in the conduct of scientific research. There is mutual benefit to communities and researchers when both parties work together throughout the scientific research process. In the IMPAACT Network, community participation occurs throughout the network, community and site levels through various mechanisms that include representation on the network committees, protocols teams and cross network community activities.

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