Manuscripts
Showing 1600 manuscripts.
Safety, Tolerability, and Pharmacokinetics of a Long-Acting Broadly Neutralizing Human Immunodeficiency Virus Type 1 (HIV-1) Monoclonal Antibody VRC01LS in HIV-1-Exposed Newborn Infants
Citation
Elizabeth McFarland, Coleen Cunningham, Petronella Muresan, Edmund Capperelli, Charlotte Perlowski, Patricia Morgan, Betsy Smith, Rohan Hazra, Lynette Purdue, Paul Harding, Gerhard Theron, Hilda Mujuru, Allison Agwu, Murli Purswani, Mobeen Rathore, Britta Flach, Alison Taylor, Bob Lin, Adrian McDermott, John Mascola, Barney Graham, IMPAACT P1112 Team. Safety, Tolerability, and Pharmacokinetics of a Long-Acting Broadly Neutralizing Human Immunodeficiency Virus Type 1 (HIV-1) Monoclonal Antibody VRC01LS in HIV-1-Exposed Newborn Infants. Journal of Infectious Diseases. 2021 Dec 01; 224(11):1916-1924. PMID: 34009371; PMCID: PMC8643399.Year
2021
Journal
Journal of Infectious Diseases
Study
P1112
Etravirine in treatment-experienced HIV-1-infected children 1 year to less than 6 years of age
Citation
Christine E MacBrayne, Richard M Rutstein, Andrew A Wiznia, Bobbie Graham, Carmelita G Alvero, Lee Fairlie, Kathryn Lypen, Kathleen H George, Ellen Townley, Jack Moye Jr., Diane G Costello, Christina A Reding, Cristina Barroso Hofer, Herta M Crauwels, Xavier Woot de Trixhe, Lotke Tambuyzer, Simon Vanveggel, Magda Opsomer, Jennifer J Kiser, IMPAACT P1090 Protocol Team. Etravirine in treatment-experienced HIV-1-infected children 1 year to less than 6 years of age. AIDS. 2021 Jul 15; 35(9):1413-1421. PMID: 33831904; PMCID: PMC8270511.Year
2021
Journal
AIDS
Study
P1090
Population Pharmacokinetics of Tenofovir in Pregnant and Postpartum Women Using Tenofovir Disoproxil Fumarate
Citation
Ahizechukwu C Eke, Kensuke Shoji, Brookie M Best , Jeremiah D Momper, Alice M Stek, Tim R Cressey, Mark Mirochnick, Edmund V Capparelli. Population Pharmacokinetics of Tenofovir in Pregnant and Postpartum Women Using Tenofovir Disoproxil Fumarate. Antimicrobial Agents and Chemotherapy. 2021 Feb 12; 65(3):e02168-20. PMID: 33318014; PMCID: PMC8092509.Year
2021
Journal
Antimicrobial Agents and Chemotherapy
Study
P1026S
Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development
Citation
Sherry Zhao, Mary Gockenbach, Manuela Grimstein, Hari Cheryl Sachs, Mark Mirochnick, Kimberly Struble, Yodit Belew, Jian Wang, Edmund V. Capparelli, Brookie M. Best, Tamara Johnson, Jeremiah D. Momper, Anil R. Maharaj. Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development. Frontiers in Pediatrics. 2021 Oct 13; 9:721059. PMID: 34722417; PMCID: PMCID: PMC8550258.Year
2021
Journal
Frontiers in Pediatrics
Study
P1026S
Pharmacokinetics of darunavir and cobicistat in pregnant and postpartum women with HIV
Citation
Jeremiah D Momper, Jiajia Wang, Alice Stek, David E Shapiro, Gwendolyn B Scott, Mary E Paul, Irma L Febo, Sandra Burchett, Elizabeth Smith, Nahida Chakhtoura, Kayla Denson, Kittipong Rungruengthanakit, Kathleen George, Derek Z Yang, Edmund V Capparelli, Mark Mirochnick, Brookie M Best, IMPAACT P1026s Protocol Team. Pharmacokinetics of darunavir and cobicistat in pregnant and postpartum women with HIV. AIDS. 2021 Jul 01; 35(8):1191-1199. PMID: 34076612; PMCID: PMC8173003.Year
2021
Journal
AIDS
Study
P1026S
Physiologically Based Pharmacokinetic Modeling Framework to Predict Neonatal Pharmacokinetics of Transplacentally Acquired Emtricitabine, Dolutegravir, and Raltegravir
Citation
Xiaomei I Liu, Jeremiah D Momper, Natella Y Rakhmanin, Dionna J Green, Gilbert J Burckart, Tim R Cressey, Mark Mirochnick, Brookie M Best, John N van den Anker, André Dallmann. Physiologically Based Pharmacokinetic Modeling Framework to Predict Neonatal Pharmacokinetics of Transplacentally Acquired Emtricitabine, Dolutegravir, and Raltegravir. Clinical Pharmacokinetics. 2021 Jun 01; 60(6):795-809. PMID: 33527213; PMCID: PMC9334904.Year
2021
Journal
Clinical Pharmacokinetics
Study
P1026S
Lopinavir and tenofovir interaction observed in non-pregnant adults altered during pregnancy
Citation
Nikki Mulligan, Engie Salama, Jeremiah D Momper, Edmund V Capparelli, Alice Stek, Nahida Chakhtoura, Mark Mirochnick, Brookie M Best, IMPAACT P1026s Protocol Team. Lopinavir and tenofovir interaction observed in non-pregnant adults altered during pregnancy. Journal of Clinical Pharmacy and Theraputics. 2021 Oct 01; 46(5):1459-1464. PMID: 34254323; PMCID: PMC8448937.Year
2021
Journal
Journal of Clinical Pharmacy and Theraputics
Study
P1026S
Comparison of dried blood spot and plasma sampling for untargeted metabolomics
Citation
Nicole H. Tobin, Aisling Murphy, Fan Li, Sean S Brummel, Taha E. Taha, Friday Saidi, Maxie Owor, Avy Violari, Dhayendre Moodley, Benjamin Chi, Kelli D. Goodman, Brian Koos, Grace M. Aldrovandi. Comparison of dried blood spot and plasma sampling for untargeted metabolomics. Metabolomics. 2021 Jun 23; 17(7):62. PMID: 34164733; PMCID: PMC8340475.Year
2021
Journal
Metabolomics
Study
1077BF, 1077FF
Machine Learning Algorithms Using Routinely Collected Data Do Not Adequately Predict Viremia to Inform Targeted Services in Postpartum Women Living With HIV
Citation
Pamela M Murnane, James Ayieko, Eric Vittinghoff, Monica Gandhi, Chaplain Katumbi, Beteniko Milala, Catherine Nakaye, Peter Kanda, Dhayendre Moodley, Mandisa E Nyati, Amy J Loftis, Mary G Fowler, Pat Flynn, Judith S Currier, Craig R Cohen. Machine Learning Algorithms Using Routinely Collected Data Do Not Adequately Predict Viremia to Inform Targeted Services in Postpartum Women Living With HIV. Journal of Acquired Immune Deficiency Syndromes. 2021 Dec 15; 88(5):439-447. PMID: 34520443; PMCID: PMC8585692.Year
2021
Journal
Journal of Acquired Immune Deficiency Syndromes
Study
1077BF, 1077FF, 1077HS
Drug susceptibility patterns of Mycobacterium tuberculosis from adults with multidrug-resistant tuberculosis and implications for a household contact preventive therapy trial
Citation
Anne-Marie Demers, Soyeon Kim, Sara McCallum, Kathleen Eisenach, Michael Hughes, Linda Naini , Alberto Mendoza-Ticona , Neeta Pradhan, Kim Narunsky, Selvamuthu Poongulali , Sharlaa Badal-Faesen, Caryn Upton, Elizabeth Smith , N Sarita Shah , Gavin Churchyard, Amita Gupta, Anneke Hesseling, Susan Swindells , ACTG A5300/IMPAACT I2003 PHOENIx Feasibility study team. Drug susceptibility patterns of Mycobacterium tuberculosis from adults with multidrug-resistant tuberculosis and implications for a household contact preventive therapy trial. BMC Infectious Diseases. 2021 Feb 24; 21(1):205. PMID: 33627075; PMCID: PMC7903693.Year
2021
Journal
BMC Infectious Diseases
Study
IMPAACT 2003/ACTG 5300