Primary Protocol Team Members
What is IMPAACT 2034?
IMPAACT 2034 is a Phase I, multi-site, open-label, pharmacokinetic (PK), safety, tolerability, and acceptability study of a single-dose of pretomanid (Pa) in infants, children, and adolescents less than 18 years of age living with or without HIV and confirmed or probable rifampicin-resistant tuberculosis. Participants will be given a single-dose of pretomanid, added to their TB treatment regimen, with intensive PK sampling. After receiving the single dose of Pa, participants will be followed for two weeks for safety.