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P1107 / Cord Blood Transplantation

Cord Blood Transplantation with CCR5delta32 Donor Cells in Persons Living with HIV who Require Bone Marrow Transplantation for any Indication and Its Observed Effects on HIV-1 Persistence

Study Status

Participants Off Study and Primary Analysis Completed

DAIDS Number

11883

IND Number

Non-IND

Clinical Trials Link

Summary

P1107 is multi-center observational study that will describe the outcomes of up to 25 participants from the US living with HIV, ages 12 months and older, who undergo transplantation with CCR5Δ32 cord blood stem cells for treatment of cancer, hematopoietic disease, or other underlying disease.

15 February 2022: IMPAACT P1107 Team Presents First Known Case of a Woman with HIV Remission

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Study Documents:

pdf
853.48 KB
pdf
1.63 MB
25 November 2020
pdf
52.57 KB

Study Chair

Study Vice-Chair

DAIDS Medical Officer

Clinical Research Manager

Data Manager

Immunologist

Laboratory Data Manager (LDM)

Laboratory Specialist

Laboratory Technologist

Statistician

Virologist

Manuscripts

HIV-1 Remission and Possible Cure in a Woman after Haplo-Cord Blood Transplant

Jingmei Hsu, Koen Van Besien, Marshall J. Glesby, Savita Pahwa, Anne Coletti, Meredith G. Warshaw, Lawrence D Petz, Theodore B. Moore, Ya Hui Chen, Suresh Pallikkuth, Adit Dhummakupt, Ruth Cortado, Amanda Golner, Frederic Bone, Maria Baldo, Marcie Riches, John W. Mellors, Nicole H. Tobin, Renee Browning, Deborah Persaud, Yvonne Bryson, IMPAACT P1107 Team. HIV-1 Remission and Possible Cure in a Woman after Haplo-Cord Blood Transplant. Cell. 2023. 186: 1115-1126.

Year

2023

Journal

Cell

Study

P1107

Abstracts

HIV-1 Remission with CCR5delta32delta32 Haplo-Cord Transplant in a US Woman: IMPAACT P1107

Conference

CROI 2022

Study

P1107

Authors

JingMei Hsu, Koen Van Besien, Marshall Glesby, Anne Coletti, Savita Pahwa, Meredith Warshaw, Amanda Golner, Fredrick Bone, Nicole Tobin, Marcie Riches, John Mellors, Renee Browning, Deborah Persaud, Yvonne Bryson, IMPAACT P1107 Team